Faculty

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You Jeong Lee
Tel : +82-54-279-8767
youjeong77@postech.ac.kr

Education

M.D., Seoul National University, College of Medicine (2002)
Ph.D., Seoul National University, College of Medicine (2010)

Career

1999~2002 : Dong-Suh Scholarship, Korea
2003~2007 : Resident in Pathology, Seoul National University Hospital, Korea
2007~2010 : Research Assistant, Seoul National University, College of Medicine, Korea
2010~2016 : Post-doctoral fellow, University of Minnesota, MN, USA
2011~2014 : Irvington Fellowship of Cancer Research Institute, USA
2015 : Keystone scholarship, T Cells: Regulation and Effector Function, Utah, USA
2015 : NIH Pathway to Independence Award (K99 AI114884)
2016 : Junior Principal Investigator, AIM / IBS Assistant Professor, POSTECH

Key Publications

1. Lineage specific effector signatures are shared amongst NKT, ILC, gd T, and helper T cells. You Jeong Lee*, Gabriel J. Starrett, Seungeun Thera Lee, Haiguang Wang, Rendong Yang, Christine Henzler, Stephen C. Jameson, & Kristin A. Hogquist*. J Immunol, 2016 15;197(4):1460-70 *Corresponding author

2. Tissue specific distribution of iNKT cells impacts their cytokine response. You Jeong Lee, Haiguang Wang, Gabriel Starrett, Vanessa Phuong, Stephen C. Jameson, Kristin A. Hogquist. Immunity, 2015, 43, 1-13

3. Steady-state production of IL-4 modulates immunity in mouse strains and is determined by lineage diversity of iNKT cells. You Jeong Lee, Keli L Holzapfel, Jinfang Zhu, Stephen C Jameson & Kristin A Hogquist. Nat Immunol. 2013, 14(11):1146-54

4. Sclerodermatous chronic graft-versus-host disease induced by host T cell-mediated autoimmune process.You Jeong Lee, Hye Sook Min, Eun Ha Kang, Hyo Jin Park, Young Ha Oh, Hong Gyun Wu, Eun-Bong Lee, Chung-Gyu Park, Sung-Soo Yoon, Seong Hoe Park, Kyeong Cheon Jung. Immunol Cell Biol. 2012, 90(3):358-67.

5. Alternative memory in the CD8 T cell lineage. You Jeong Lee, Stephen C. Jameson and Kristin A. Hogquist. Trends Immunol. 2011, 32(2):50-6

6. MHC class II–restricted PLZF expressing CD4+ T cells convert CD8+ T cells into an innate phenotype. Hye Sook Min*, You Jeong Lee*, Yoon Kyeong Jeon, Byung Hyun Kang, Eun Ji Kim, Kyeong Cheon Jung, Cheong-Hee Chang, Seong Hoe Park. J Immunol. 2011, 186(10):5749-57. (*equal contribution)

7. Generation of PLZF+ CD4+ T cells via MHC class II–dependent thymocyte–thymocyte interaction is a physiological process in humans. You Jeong Lee, Yoon Kyung Jeon, Byung Hyun Kang, Doo Hyun Chung, Chung-Gyu Park, Hee Young Shin, Kyeong Cheon Jung, and Seong Hoe Park. J Exp Med. 2010 18;207(1):237-46.

8. MHC class II-dependent T–T interactions create a diverse, functional and immunoregulatory reaction circle. You Jeong Lee, Kyeong Cheon Jung and Seong Hoe Park. Immunol Cell Biol. 2009 87(1):65-71